In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid

In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid

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3D Ti-mesh has been coated with bioceramics under different coating conditions, such as material compositions and micro-porosity, using a dip casting method.Hydroxyapatite (HA), micro-HA particles (HAp), a bioglass (BG) and their different mixtures together with polymer additives were used to control ckf snafu 2.0 HA-coating microstructures.Layered composites with the following coating-to-substrate designs, such as BG/Ti, HA + BG/BG/Ti and HAp + BG/BG/Ti, were fabricated.

The bioactivity of these coated composites and the uncoated Ti-mesh substrate was then investigated in a simulated body fluid (SBF).The Ti-mesh substrate and BG/Ti composite did not induce biomimetic apatite deposition when they were immersed in SBF for the selected BG, a pressable dental ceramic, used in this study.After seven days in SBF, an apatite layer was formed on both HA + BG/BG/Ti and HAp + BG/BG/Ti composites.

The difference is the apatite layer on the HAp + BG/BG/Ti composite was rougher and contained more purple and black wigs micro-pores, while the apatite layer on the HA + BG/BG/Ti composite was dense and smooth.The formation of biomimetic apatite, being more bioresorbable, is favored for bone regeneration.